DrugApprovals KP (opens the knowledge source's documentation in a new tab) version 1.23.4 latest
This relationship states that ethambutol (opens ebi.ac.uk in a new tab) was applied off label to treat choroiditis (opens monarchinitiative.org in a new tab).
67c98f98-5648-3ed1-bc11-8c5b4b5fee77
Download KGX
ethambutol (opens ebi.ac.uk in a new tab) CHEBI:94436 (opens ebi.ac.uk in a new tab) , a SmallMolecule (opens biolink.github.io in a new tab), was applied off label to treat choroiditis (opens monarchinitiative.org in a new tab) MONDO:0001280 (opens monarchinitiative.org in a new tab) , a Disease (opens biolink.github.io in a new tab). This observation is machine generated. The entire dataset underwent manual QC with some human validation. This association was generated by DrugApprovals KP (opens biolink.github.io in a new tab), which integrates the FDA Adverse Event Reporting System (FAERS) (opens biolink.github.io in a new tab), DailyMed (opens biolink.github.io in a new tab), and Canada Vigilance Adverse Reaction Database (opens canada.ca in a new tab).
No FDA application numbers are recorded for this association. FAERS and Canada Vigilance record 31 cases of this usage. No structured-product-label set identifiers are recorded for this association.
Try searching DailyMed for labels mentioning ethambutol (opens dailymed.nlm.nih.gov in a new tab), labels mentioning choroiditis (opens dailymed.nlm.nih.gov in a new tab), or labels mentioning both ethambutol and choroiditis (opens dailymed.nlm.nih.gov in a new tab).
Stored versions
Changes
1 field differ between infores:drugapprovals-kp-1.23.3 and infores:drugapprovals-kp-1.23.4 (+ added / - removed):
Changed lists
-
Knowledge sources
-
added
{"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://linkouts.skyelanegoetz.com/edges/67c98f98-5648-3ed1-bc11-8c5b4b5fee77"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]} -
removed
{"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://db.systemsbiology.net/gestalt/cgi-pub/KGinfo.pl?id=67c98f98-5648-3ed1-bc11-8c5b4b5fee77"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]}
-
added
About this knowledge graph
The DrugApprovals KP curates assertions of FDA- and EMA-approved treatment relationships, usages observed in FAERS and Health Canada's Canada Vigilance database and applied to treat, and contraindications text-mined from DailyMed labeling; these assertions are derived from DailyMed, Drugs@FDA, FAERS, Canada Vigilance, and the EMA medicines registry.
Something wrong with this relationship? Open an issue. (opens GitHub in a new tab)