For research use. These pages describe what a knowledge graph asserts; they are not clinical advice and must not guide the treatment of a patient.

DrugApprovals KP (opens the knowledge source's documentation in a new tab) version 1.23.3

This relationship states that ethambutol (opens ebi.ac.uk in a new tab) was applied off label to treat choroiditis (opens monarchinitiative.org in a new tab).

67c98f98-5648-3ed1-bc11-8c5b4b5fee77 Download KGX

Known issue in release 1.23.3. The per-edge linkouts on db.systemsbiology.net do not exist for this version.

ethambutol (opens ebi.ac.uk in a new tab) , a SmallMolecule (opens biolink.github.io in a new tab), was applied off label to treat choroiditis (opens monarchinitiative.org in a new tab) , a Disease (opens biolink.github.io in a new tab). This observation is machine generated. The entire dataset underwent manual QC with some human validation. This association was generated by DrugApprovals KP (opens biolink.github.io in a new tab), which integrates the FDA Adverse Event Reporting System (FAERS) (opens biolink.github.io in a new tab), DailyMed (opens biolink.github.io in a new tab), and Canada Vigilance Adverse Reaction Database (opens canada.ca in a new tab).

No FDA application numbers are recorded for this association. FAERS and Canada Vigilance record 31 cases of this usage. No structured-product-label set identifiers are recorded for this association.

Try searching DailyMed for labels mentioning ethambutol (opens dailymed.nlm.nih.gov in a new tab), labels mentioning choroiditis (opens dailymed.nlm.nih.gov in a new tab), or labels mentioning both ethambutol and choroiditis (opens dailymed.nlm.nih.gov in a new tab).

Stored versions

Changes

This is the oldest stored version; there is nothing earlier to compare it with.

About this knowledge graph

The DrugApprovals KP curates assertions of FDA- and EMA-approved treatment relationships, usages observed in FAERS and Health Canada's Canada Vigilance database and applied to treat, and contraindications text-mined from DailyMed labeling; these assertions are derived from DailyMed, Drugs@FDA, FAERS, Canada Vigilance, and the EMA medicines registry.

Something wrong with this relationship? Open an issue. (opens GitHub in a new tab)