For research use. These pages describe what a knowledge graph asserts; they are not clinical advice and must not guide the treatment of a patient.

DrugApprovals KP (opens the knowledge source's documentation in a new tab) version 1.23.4 latest

This relationship states that Bicarbonate Ions (opens identifiers.org in a new tab) has been approved for treating cardiac arrest (opens monarchinitiative.org in a new tab), in the blood.

262543fb-27c3-32fd-ae00-d0b3949b5440 Download KGX

Bicarbonate Ions (opens identifiers.org in a new tab) , a ChemicalEntity (opens biolink.github.io in a new tab), has been approved for treating cardiac arrest (opens monarchinitiative.org in a new tab) , a Disease (opens biolink.github.io in a new tab), in the blood. This assertion is machine-generated and human-validated. This association was generated by DrugApprovals KP (opens biolink.github.io in a new tab), which integrates the FDA Adverse Event Reporting System (FAERS) (opens biolink.github.io in a new tab), DailyMed (opens biolink.github.io in a new tab), the EMA medicines registry (opens ema.europa.eu in a new tab), and the EMA EPAR (opens ema.europa.eu in a new tab).

DrugApprovals KP asserts this association is approved for the indicated condition. Regulatory approval for this association is documented under ANDA217594 (opens fda.report in a new tab). This association is documented on the product labels 3867f743-c2cf-a646-e063-6394a90a82e1 (opens dailymed.nlm.nih.gov in a new tab), 4f97d398-2118-0874-e063-6394a90a4ad1 (opens dailymed.nlm.nih.gov in a new tab), 5ae65432-04a1-4b6b-8536-2535064fc782 (opens dailymed.nlm.nih.gov in a new tab) .

Try searching DailyMed for labels mentioning Bicarbonate Ions (opens dailymed.nlm.nih.gov in a new tab), labels mentioning cardiac arrest (opens dailymed.nlm.nih.gov in a new tab), or labels mentioning both Bicarbonate Ions and cardiac arrest (opens dailymed.nlm.nih.gov in a new tab).

Stored versions

Changes

1 field differ between infores:drugapprovals-kp-1.23.3 and infores:drugapprovals-kp-1.23.4 (+ added / - removed):

Changed lists

  • Knowledge sources
    • added {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://linkouts.skyelanegoetz.com/edges/262543fb-27c3-32fd-ae00-d0b3949b5440"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:ema","infores:epar"]}
    • removed {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://db.systemsbiology.net/gestalt/cgi-pub/KGinfo.pl?id=262543fb-27c3-32fd-ae00-d0b3949b5440"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:ema","infores:epar"]}

About this knowledge graph

The DrugApprovals KP curates assertions of FDA- and EMA-approved treatment relationships, usages observed in FAERS and Health Canada's Canada Vigilance database and applied to treat, and contraindications text-mined from DailyMed labeling; these assertions are derived from DailyMed, Drugs@FDA, FAERS, Canada Vigilance, and the EMA medicines registry.

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