For research use. These pages describe what a knowledge graph asserts; they are not clinical advice and must not guide the treatment of a patient.

DrugApprovals KP (opens the knowledge source's documentation in a new tab) version 1.23.4 latest

This relationship states that clonidine Transdermal System has been applied to treat hypertensive disorder (opens monarchinitiative.org in a new tab).

7d5451c8-d3a9-3e27-823b-b91b7242f2b3 Download KGX

clonidine Transdermal System , a Drug (opens biolink.github.io in a new tab), has been applied to treat hypertensive disorder (opens monarchinitiative.org in a new tab) , a Disease (opens biolink.github.io in a new tab). This observation is machine generated. The entire dataset underwent manual QC with some human validation. This association was generated by DrugApprovals KP (opens biolink.github.io in a new tab), which integrates Canada Vigilance Adverse Reaction Database (opens canada.ca in a new tab), DailyMed (opens biolink.github.io in a new tab), and the FDA Adverse Event Reporting System (FAERS) (opens biolink.github.io in a new tab).

DrugApprovals KP asserts this association is approved for the indicated condition. No FDA application numbers are recorded for this association. FAERS and Canada Vigilance record 411 cases of this usage. No structured-product-label set identifiers are recorded for this association.

Try searching DailyMed for labels mentioning clonidine Transdermal System (opens dailymed.nlm.nih.gov in a new tab), labels mentioning hypertensive disorder (opens dailymed.nlm.nih.gov in a new tab), or labels mentioning both clonidine Transdermal System and hypertensive disorder (opens dailymed.nlm.nih.gov in a new tab).

Stored versions

Changes

1 field differ between infores:drugapprovals-kp-1.23.3 and infores:drugapprovals-kp-1.23.4 (+ added / - removed):

Changed lists

  • Knowledge sources
    • added {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://linkouts.skyelanegoetz.com/edges/7d5451c8-d3a9-3e27-823b-b91b7242f2b3"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]}
    • removed {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://db.systemsbiology.net/gestalt/cgi-pub/KGinfo.pl?id=7d5451c8-d3a9-3e27-823b-b91b7242f2b3"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]}

About this knowledge graph

The DrugApprovals KP curates assertions of FDA- and EMA-approved treatment relationships, usages observed in FAERS and Health Canada's Canada Vigilance database and applied to treat, and contraindications text-mined from DailyMed labeling; these assertions are derived from DailyMed, Drugs@FDA, FAERS, Canada Vigilance, and the EMA medicines registry.

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