DrugApprovals KP (opens the knowledge source's documentation in a new tab) version 1.23.4 latest

This relationship states that Tygacil (opens identifiers.org in a new tab) was applied off label to treat mycobacterial infectious disease (opens monarchinitiative.org in a new tab).

897ef74c-7451-33a0-b314-accff185d73c Download KGX

Tygacil (opens identifiers.org in a new tab) , a ChemicalEntity (opens biolink.github.io in a new tab), was applied off label to treat mycobacterial infectious disease (opens monarchinitiative.org in a new tab) , a Disease (opens biolink.github.io in a new tab). This observation is machine generated. The entire dataset underwent manual QC with some human validation. This association was generated by DrugApprovals KP (opens biolink.github.io in a new tab), which integrates the FDA Adverse Event Reporting System (FAERS) (opens biolink.github.io in a new tab), DailyMed (opens biolink.github.io in a new tab), and Canada Vigilance Adverse Reaction Database (opens canada.ca in a new tab).

No FDA application numbers are recorded for this association. FAERS and Canada Vigilance record 11 cases of this usage. No structured-product-label set identifiers are recorded for this association.

Try searching DailyMed for labels mentioning Tygacil (opens dailymed.nlm.nih.gov in a new tab), labels mentioning mycobacterial infectious disease (opens dailymed.nlm.nih.gov in a new tab), or labels mentioning both Tygacil and mycobacterial infectious disease (opens dailymed.nlm.nih.gov in a new tab).

Stored versions

Changes

1 field differ between infores:drugapprovals-kp-1.23.3 and infores:drugapprovals-kp-1.23.4 (+ added / - removed):

Changed lists

Knowledge sources
- added {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://linkouts.skyelanegoetz.com/edges/897ef74c-7451-33a0-b314-accff185d73c"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]}
- removed {"resource_id":"infores:drugapprovals-kp","resource_role":"primary_knowledge_source","source_record_urls":["https://db.systemsbiology.net/gestalt/cgi-pub/KGinfo.pl?id=897ef74c-7451-33a0-b314-accff185d73c"],"upstream_resource_ids":["infores:dailymed","infores:faers","infores:canada-vigilance"]}

About this knowledge graph

The DrugApprovals KP curates assertions of FDA- and EMA-approved treatment relationships, usages observed in FAERS and Health Canada's Canada Vigilance database and applied to treat, and contraindications text-mined from DailyMed labeling; these assertions are derived from DailyMed, Drugs@FDA, FAERS, Canada Vigilance, and the EMA medicines registry.

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